Youseung Shin: search on Z-Library

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1

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

Woldt, Estelle, Sebti, Yasmine, Solt, Laura A, Duhem, Christian, Lancel, Steve, Eeckhoute, Jérôme, Hesselink, Matthijs K C, Paquet, Charlotte, Delhaye, Stéphane, Shin, Youseung, Kamenecka, Theodore M,

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 855 KB

english, 2013

2

Design, Synthesis, and Biological Evaluation of Indole Biphenylcarboxylic Acids as PPARγ Antagonists

Asteian, Alice, Blayo, Anne-Laure, He, Yuanjun, Koenig, Marcel, Shin, Youseung, Kuruvilla, Dana S., Corzo, Cesar A., Cameron, Michael D., Lin, Li, Ruiz, Claudia, Khan, Susan, Kumar, Naresh, Busby, Sco

Journal:

ACS Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 668 KB

english, 2015

3

Simplified Discodermolide Analogues: Synthesis and Biological Evaluation of 4- e pi -7-Dehydroxy-14,16-didemethyl-(+)-discodermolides as Microtubule-Stabilizing Agents

Choy, Nakyen, Shin, Youseung, Nguyen, Phu Qui, Curran, Dennis P., Balachandran, Raghavan, Madiraju, Charitha, Day, Billy W.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 406 KB

english, 2003

4

Discodermolide/Dictyostatin Hybrids: Synthesis and Biological Evaluation

Shin, Youseung, Choy, Nakyen, Turner, Tiffany R., Balachandran, Raghavan, Madiraju, Charitha, Day, Billy W., Curran, Dennis P.

Journal:

Organic Letters

Year:

2003

File:

PDF, 4 KB

2003

5

Systems Cell Biology Knowledge Created from High Content Screening

Giuliano, Kenneth A., Cheung, Wing S., Curran, Dennis P., Day, Billy W., Kassick, Andrew J., Lazo, John S., Nelson, Scott G., Shin, Youseung, Taylor, D. Lansing

Journal:

Assay and Drug Development Technologies

Year:

2005

Language:

english

File:

PDF, 659 KB

english, 2005

6

Discovery of LB30057, a benzamidrazone-based selective oral thrombin inhibitor

Yeong Soo Oh, Mikyung Yun, Sang Yeul Hwang, Seongwon Hong, Youseung Shin, Koo Lee, Kyung Hee Yoon, Yung Joon Yoo, Dong Soo Kim, Sun Hwa Lee, Yong Hee Lee, Hee Dong Park, Chang Ho Lee, Sang Koo Lee, Sa

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 286 KB

english, 1998

7

Structural Modification of an Orally Active Thrombin Inhibitor, LB30057: Replacement of the D-Pocket-binding Naphthyl Moiety

Koo Lee, Sang Yeul Hwang, Seongwon Hong, Chang Yong Hong, Chang-Seok Lee, Youseung Shin, Sangsoo Kim, Mikyung Yun, Yung Joon Yoo, Myunggyun Kang, Yeong Soo Oh

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 343 KB

english, 1998

8

Enantioselective Total Synthesis of (+)-Gliocladin C

Overman, Larry E., Shin, Youseung

Journal:

Organic Letters

Year:

2007

Language:

english

File:

PDF, 81 KB

english, 2007

9

ChemInform Abstract: 3-Aryl-4-aryloyl-1-(1H-imidazol-5-yl)methylpyrrole, a Novel Class of Farnesyltransferase Inhibitors.

Hyunil Lee, Jinho Lee, Youseung Shin, Wonhee Jung, Jong-Hyun Kim, Kiwon Park, Seonggu Ro, Hyun-Ho Chung, Jong Sung Koh

Journal:

Year:

2002

File:

PDF, 33 KB

2002

10

Total Synthesis and Biological Evaluation of C16 Analogs of (−)-Dictyostatin

Jung, Won-Hyuk, Harrison, Cristian, Shin, Youseung, Fournier, Jean-Hugues, Balachandran, Raghavan, Raccor, Brianne S., Sikorski, Rachel P., Vogt, Andreas, Curran, Dennis P., Day, Billy W.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 385 KB

english, 2007

11

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

Solt, Laura A., Wang, Yongjun, Banerjee, Subhashis, Hughes, Travis, Kojetin, Douglas J., Lundasen, Thomas, Shin, Youseung, Liu, Jin, Cameron, Michael D., Noel, Romain

Journal:

Year:

2012

Language:

english

File:

PDF, 644 KB

english, 2012

12

Total Synthesis of (−)-Dictyostatin: Confirmation of Relative and Absolute Configurations

Youseung Shin, Jean-Hugues Fournier, Yoshikazu Fukui, Arndt M. Brückner, Dennis P. Curran

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 216 KB

english, 2004

13

Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors

Romain Noël, Youseung Shin, Xinyi Song, Yuanjun He, Marcel Koenig, Weimin Chen, Yuan Yuan Ling, Li Lin, Claudia H. Ruiz, Phil LoGrasso, Michael D. Cameron, Derek R. Duckett, Theodore M. Kamenecka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 623 KB

english, 2011

14

Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors

Youseung Shin, Weiming Chen, Jeff Habel, Derek Duckett, Yuan Yuan Ling, Marcel Koenig, Yuanjun He, Tomas Vojkovsky, Philip LoGrasso, Theodore M. Kamenecka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 493 KB

english, 2009

15

Synthesis and SAR of tetrahydroisoquinolines as Rev-erbα agonists

Romain Noel, Xinyi Song, Youseung Shin, Subhashis Banerjee, Douglas Kojetin, Li Lin, Claudia H. Ruiz, Michael D. Cameron, Thomas P. Burris, Theodore M. Kamenecka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 3.39 MB

english, 2012

16

Synthesis and Biological Evaluation of (−)-16-Normethyldictyostatin: A Potent Analogue of (−)-Dictyostatin †

Shin, Youseung, Fournier, Jean-Hugues, Balachandran, Raghavan, Madiraju, Charitha, Raccor, Brianne S., Zhu, Guangyu, Edler, Michael C., Hamel, Ernest, Day, Billy W., Curran, Dennis P.

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 86 KB

english, 2005

17

Fluorous Mixture Synthesis of (−)-Dictyostatin and Three Stereoisomers

Fukui, Yoshikazu, Brückner, Arndt M., Shin, Youseung, Balachandran, Raghavan, Day, Billy W., Curran, Dennis P.

Journal:

Organic Letters

Year:

2006

Language:

english

File:

PDF, 132 KB

english, 2006

18

Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour

Banerjee, Subhashis, Wang, Yongjun, Solt, Laura A., Griffett, Kristine, Kazantzis, Melissa, Amador, Ariadna, El-Gendy, Bahaa M., Huitron-Resendiz, Salvador, Roberts, Amanda J., Shin, Youseung, Kamenec

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 5.60 MB

english, 2014

19

Titelbild: Total Synthesis and Configurational Assignment of (−)-Dictyostatin, a Microtubule-Stabilizing Macrolide of Marine Sponge Origin / Total Synthesis of (−)-Dictyostatin: Confirmation of Relative and Absolute Configurations (Angew. Chem. 35/2004)

Ian Paterson, Robert Britton, Oscar Delgado, Arndt Meyer, Karine G. Poullennec, Youseung Shin, Jean-Hugues Fournier, Yoshikazu Fukui, Arndt M. Brückner, Dennis P. Curran

Journal:

Angewandte Chemie

Year:

2004

File:

PDF, 60 KB

2004

20

Total Synthesis of (−)-Dictyostatin: Confirmation of Relative and Absolute Configurations

Youseung Shin, Jean-Hugues Fournier, Yoshikazu Fukui, Arndt M. Brückner, Dennis P. Curran

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 217 KB

english, 2004

21

Cover Picture: Total Synthesis and Configurational Assignment of (−)-Dictyostatin, a Microtubule-Stabilizing Macrolide of Marine Sponge Origin / Total Synthesis of (−)-Dictyostatin: Confirmation of Relative and Absolute Configurations (Angew. Chem. Int. Ed. 35/2004)

Ian Paterson, Robert Britton, Oscar Delgado, Arndt Meyer, Karine G. Poullennec, Youseung Shin, Jean-Hugues Fournier, Yoshikazu Fukui, Arndt M. Brückner, Dennis P. Curran

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 59 KB

english, 2004

22

SR2067 Reveals a Unique Kinetic and Structural Signature for PPARγ Partial Agonism

van Marrewijk, Laura M., Polyak, Steven W., Hijnen, Marcel, Kuruvilla, Dana, Chang, Mi Ra, Shin, Youseung, Kamenecka, Theodore M., Griffin, Patrick R., Bruning, John B.

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 4.28 MB

english, 2016

23

Synthesis and biological evaluation of (−)-dictyostatin and stereoisomers

Youseung Shin, Jean-Hugues Fournier, Arndt Brückner, Charitha Madiraju, Raghavan Balachandran, Brianne S. Raccor, Michael C. Edler, Ernest Hamel, Rachel P. Sikorski, Andreas Vogt, Billy W. Day, Dennis

Journal:

Year:

2007

Language:

english

File:

PDF, 969 KB

english, 2007

24

Total Synthesis of (-)-Dictyostatin: Confirmation of Relative and Absolute Configurations.

Youseung Shin, Jean-Hugues Fournier, Yoshikazu Fukui, Arndt M. Brueckner, Dennis P. Curran

Journal:

Year:

2004

File:

PDF, 7 KB

2004

25

Tubulin Assembly, Taxoid Site Binding, and Cellular Effects of the Microtubule-Stabilizing Agent Dictyostatin †

Madiraju, Charitha, Edler, Michael C., Hamel, Ernest, Raccor, Brianne S., Balachandran, Raghavan, Zhu, Guangyu, Giuliano, Kenneth A., Vogt, Andreas, Shin, Youseung, Fournier, Jean-Hugues, Fukui, Yoshi

Journal:

Year:

2005

Language:

english

File:

PDF, 384 KB

english, 2005

26

Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) Inhibitors

Yuanjun He, Theodore M. Kamenecka, Youseung Shin, Xinyi Song, Rong Jiang, Romain Noel, Derek Duckett, Weimin Chen, Yuan Yuan Ling, Michael D. Cameron, Li Lin, Susan Khan, Marcel Koenig, Philip V. LoGr

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 2.52 MB

english, 2011

27

Design and synthesis of 1-aryl-5-anilinoindazoles as c-Jun N-terminal kinase inhibitors

Jiang, Rong, Frackowiak, Bozena, Shin, Youseung, Song, Xinyi, Chen, Weimin, Lin, Li, Cameron, Michael D., Duckett, Derek R., Kamenecka, Theodore M.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 2.53 MB

english, 2013

28

3-Aryl-4-aryloyl-1-(1H-imidazol-5-yl)methylpyrrole, a novel class of farnesyltransferase inhibitors

Hyunil Lee, Jinho Lee, Youseung Shin, Wonhee Jung, Jong-Hyun Kim, Kiwon Park, Seonggu Ro, Hyun-Ho Chung, Jong Sung Koh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 97 KB

english, 2001

29

Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα

Youseung Shin, Romain Noel, Subhashis Banerjee, Douglas Kojetin, Xinyi Song, Yuanjun He, Li Lin, Michael D. Cameron, Thomas P. Burris, Theodore M. Kamenecka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 3.64 MB

english, 2012

30

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

Choi, Jang Hyun, Banks, Alexander S., Kamenecka, Theodore M., Busby, Scott A., Chalmers, Michael J., Kumar, Naresh, Kuruvilla, Dana S., Shin, Youseung, He, Yuanjun, Bruning, John B., Marciano, David P

Journal:

Year:

2011

Language:

english

File:

PDF, 768 KB

english, 2011

31

An alternate binding site for PPARγ ligands

Hughes, Travis S., Giri, Pankaj Kumar, de Vera, Ian Mitchelle S., Marciano, David P., Kuruvilla, Dana S., Shin, Youseung, Blayo, Anne-Laure, Kamenecka, Theodore M., Burris, Thomas P., Griffin, Patrick

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 8.09 MB

english, 2014

32

Confirmation of a linkage between H-Ras and MMP-13 expression as well as MMP-9 by chemical genomic approach

Su-Kyung Lee, Jung Min Kim, Mi-Young Lee, Kwang-Hee Son, Young Il Yeom, Cheol-Hee Kim, Youseung Shin, Jong Sung Koh, Dong Cho Han, Byoung-Mog Kwon

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 1.11 MB

english, 2006

33

A novel class of highly potent, selective, and non-peptidic inhibitor of ras farnesyltransferase (FTase)

Hyunil Lee, Jinho Lee, Sangkyun Lee, Youseung Shin, Wonhee Jung, Jong-Hyun Kim, Kiwon Park, Kwihwa Kim, Heung Soo Cho, Seonggu Ro, Sunhwa Lee, ShinWu Jeong, Taesaeng Choi, Hyun-Ho Chung, Jong Sung Koh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 153 KB

english, 2001

34

Synthesis and Biological Evaluation of (-)-16-Normethyldictyostatin: A Potent Analogue of (-)-Dictyostatin.

Youseung Shin, Jean-Hugues Fournier, Raghavan Balachandran, Charitha Madiraju, Brianne S. Raccor, Guangyu Zhu, Michael C. Edler, Ernest Hamel, Billy W. Day, Dennis P. Curran

Journal:

Year:

2005

File:

PDF, 12 KB

2005

35

Discodermolide/Dictyostatin Hybrids: Synthesis and Biological Evaluation†

Shin, Youseung, Choy, Nakyen, Balachandran, Raghavan, Madiraju, Charitha, Day, Billy W., Curran, Dennis P.

Journal:

Organic Letters

Year:

2002

Language:

english

File:

PDF, 120 KB

english, 2002

36

Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors

Jin, Zhuang, Khan, Pasha, Shin, Youseung, Wang, Jingyi, Lin, Li, Cameron, Michael D., Lindstrom, Jon M., Kenny, Paul J., Kamenecka, Theodore M.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 945 KB

english, 2014

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